Kinetic Investigations To Enable Development of a Robust Radical Benzylic Bromination for Commercial Manufacturing of AMG 423 Dihydrochloride Hydrate

During development of a radical benzylic bromination, observation of polymerized byproducts and variation in isolated yields warranted an in-depth mechanistic investigation to ensure process understanding and robustness. Read how in-situ kinetic studies using multinuclear CryoFree NMR spectroscopy with an HTS-110 magnet leads to an enhancement in manufacturing yield of approximately 15% in the full article at ACSPublications.

Please note a subscription may be needed to read the full text.

Application of the New 400 MHz High-Temperature Superconducting (HTS) Power-Driven Magnet NMR Technology for Online Reaction Monitoring: Proof of Concept with a Ring-Closing Metathesis (RCM) Reaction

Monitoring chemical reactions by nuclear magnetic resonance (NMR) is an established and valuable approach for process understanding, robustness, scalability, and control in the pharmaceutical industry. Understanding speciation, reaction rates, and reaction completion times provides information on how to improve a chemical process, leading to increased quality and quantity of the desired product.

HTS-110's Donald Pooke has co-authored this article which you can read at ACSPublications

Please note a subscription may be needed to read the full text.

HTS-110 CryoSaver Current Leads Video

Check out our recently published video HTS-110 CryoSaver Current Leads, demonstrates a little around how our current leads are made, their uses and what makes our current leads consistently reliable and the best in market.

Polarized neutron diffraction using a novel high‐Tc superconducting magnet on the single‐crystal diffractometer POLI at MLZ

The polarized single‐crystal diffractometer POLI is the first neutron scattering instrument routinely using 3He spin filters both to produce and to analyse neutron polarization, and it employs an HTS-110 magnet. Click here to download a PDF of this paper.


HTS-110 will be exhibiting at CGS17 on August 31 - September 4, 2020 in Grenoble, France. 

Learn more about CGS17 or contact HTS-110 to organise a meeting at CGS17.

Intermag 2020

HTS-110 will be exhibiting at Intermag 2020 on 4-8th May in Montreal, Canada. Booth #16

Learn more about Intermag or contact HTS-110 to organise a meeting at Intermag.

APS 2020

HTS-110 will be exhibiting at APS 2020 on 2-6th March in Denver, Colorado. Join us at booth #1304.

Learn more about APS or contact HTS-110 and organise a meeting at APS.

Polarized Neutron Scattering Magnet

We are delighted to announce we have been awarded a contract to supply a 3T Horizontal Magnet to United Kingdom Research and Innovation (UKRI). Read more about the magnet here

Turning off your HTS-110 Superconducting Electromagnet

Considering turning off your HTS-110 Superconducting magnet over the holiday period? We have created a safe and efficient guide for switching off your magnet. Click here to download the guide.

12 Tesla Split-Coil Magnet System

We are excited to announce we have shipped our highest field magnet to date, an HTS-110 12 tesla split-coil system to be used as a research tool in the measurement of current carrying capacities of the high-transition temperature superconducting wires. Read more about the magnet here

Bringing a cryogen-free 400 MHz HTS NMR spectrometer into a chemistry lab, a discussion with Maria Silva Elipe

An interview with Maria Silva Elipe regarding an HTS-110 designed and manufactured 400 MHz liquid cryogen-free magnet and its use in Maria's chemistry laboratory. Read the interview here

Contract to supply X-Ray Scattering Magnet

We are delighted to announce we have been selected to provide a custom-designed magnet to the prestigious Brookhaven National Laboratory. Read more in our article about the magnet.

EUCAS 2019

SEC, Glasgow

1st-5th September 2019

EUCAS 2019 is the 14th European Conference on Applied Superconductivity and is being held at the Scottish Event Campus (SEC) on the banks of the River Clyde in Glasgow. We are excited to share a booth with AF Cryo and Robinson Research Institute.

REXS 2019

Atlantis Hotel and Conference Center, Riverhead, Long Island, NY
June 17–21, 2019

Following the success of the past editions (DESY 2016, Oxford 2013, Aussois 2011), the 4th international conference on Resonant Elastic X-ray Scattering will be hosted outside Europe for the first time. The goal of the conference is to bring together the expanding REXS community, to share recent scientific achievements, reporting on current experimental capabilities, and discussing future challenges and opportunities. Particular attention will be focused on multimodality and x-ray coherence in REXS. A series of introductory lessons and tutorials will be dedicated to students on the first day of the conference. A tour of NSLS-II will be available.

Performance of New 400 MHz HTS Power-driven Magnet NMR Technology on Cinacalcet HCL Typical API in Pharma

This presentation was given at PANIC NMR 2018.

You can read and download it online at

APS March Meeting 2019

Boston, MA

March 4 - 8th

From March 4 to 8, Boston will transform into the hub of physics as more than 11,000 attendees arrive for the APS March Meeting 2019. Showcase your work for a global audience of physicists, scientists, and students representing 28 APS units and committees to explore groundbreaking research from industry, academia, and major labs.


Washington, DC

January 14-18th

The Joint MMM-Intermag Conference, convened every three years, is the combination of two annual premiere international conferences on magnetism: the IEEE International Magnetics Conference (INTERMAG) and the Conference on Magnetism and Magnetic Materials (MMM). The Conference includes all aspects of fundamental and applied magnetism, with sessions reviewing the latest advances in magnetic materials, emerging applications, new phenomena, spin electronics, energy and power applications, biomagnetism and much more.

ASC 2018 - Applied Superconductivity Conference

Seattle, Washington

October 28 - November 2nd

HTS-110 is attending ASC however we will not have a stand, if you would like to meet with us at ASC please contact us!

Structure elucidation capabilities on typical pharmaceutical drugs by new nuclear magnetic resonance technology: a 400 MHz high-temperature superconducting power-driven magnet NMR system

Nuclear magnetic resonance (NMR) is a powerful technique for the structure elucidation of organic molecules and significantly important in the pharmaceutical industry supporting the discovery and development of drug substances or active pharmaceutical ingredients (APIs).

HTS-110's Donald Pooke has co-authored this article which you can read at tandfonline

Please note a subscription may be needed to read the full text.

ISSE Workshops Berlin 2018 Presentations by Dr. Taotao Huang

At the recent ISSE Workshops, HTS-110's Taotao gave two presentations, you can download these presentations below.

A Passively Shielded HTS Magnet for Polarized Neutron Scattering

Compact HTS Magnets for Synchrotron X-ray Experiments

R&D of applied superconductivity by a small business: experiences and future perspective

In this paper we review the developments of HTS magnet technology and applications leading to a range of niche application areas, from sample environments for synchrotron and neutron beamlines and other materials analysis applications, through to developments for the demanding realm of magnetic resonance, all of which leverage the benefits of high current density relative to copper and a relatively high operating temperature compared to the low-temperature superconductors.

This paper was published in Journal of Physics: Conference Series and is available with open access through IOPscience.

Magnetic Resonance in Chemistry : MRC

Performance of new 400-MHz HTS power-driven magnet NMR technology on typical pharmaceutical API, cinacalcet HCl.

Donald Pooke has co-authored this article about a 400Mhz NMR produced by HTS-110. You can read this journal article at Europe PMC or at Wiley Online Library. Please note a subscription may be needed to read the full text.

Synchrotron Radiation Instrumentation (SRI 2018)

Taipei, Taiwan
June 10-15th

The 13th International Conference on Synchrotron Radiation Instrumentation (SRI 2018) will be hosted by the National Synchrotron Radiation Research Center (NSRRC) from June 10 to 15, 2018. A 5-day scientific program will feature the invited and contributed oral presentations in plenary and parallel sessions, poster and exhibition sessions, and a tour to the recently opened 3-GeV facility, Taiwan Photon Source (TPS) at NSRRC.

Venue: Taipei International Convention Center

See HTS-110 Neutron & X-Ray Instruments

APS March Meeting

Los Angeles
March 5 - 9th

Booth# 106

The APS March Meeting 2018 will bring together nearly 10,000 physicists, scientists, and students from all over the world to share groundbreaking research from industry, universities, and major labs. The meeting highlights a wide range of topics from 26 participating APS units.

Venue: Los Angeles Convention Center (LACC)

Headquarter Hotel: JW Marriott Hotel Los Angeles

PANIC 2018 - Practical Applications of NMR in Industry Conference

San Diego, California

March 4 - 8th

HTS-110 is attending PANIC however we will not have a stand, if you would like to meet with us at PANIC please contact us!

HTS-110 Presentation at ISS 2017

Research and Development of applied superconductivity by a small business: experience and future perspective.

click here to download the presentation.


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